Matrigen LipoExosome Prickle Permeate Cream
50ml
Matrigen LipoExosome Prickle Permeate Cream is an advanced Korean “liquid microneedling” cream formulated with spicules (marine sponge micro-needles), exosomes, PDRN, and skin-repair ingredients. It is designed to enhance ingredient penetration, stimulate skin renewal, improve elasticity, and strengthen the skin barrier while providing gentle exfoliation.
This innovative cream uses microscopic hydrolyzed sponge spicules that create temporary microchannels in the skin. These channels help deliver active ingredients such as PDRN and exosomes deeper into the skin, supporting regeneration, collagen synthesis, and improved skin texture. Users typically experience a mild prickling sensation during application, which is a normal effect of the spicules.
Key Active Ingredients
- PDRN (Sodium DNA) – supports skin regeneration and collagen production.
- Hydrolyzed Sponge (Spicules) – provides a microneedling-like effect that enhances absorption and promotes skin renewal.
- Lactobacillus Extracellular Vesicles (Exosomes) – help support skin repair and barrier function.
- Centella Asiatica Vesicles & Madecassoside – soothe irritation and support healing.
- Niacinamide – brightens skin tone and helps reduce pigmentation.
- Adenosine – improves the appearance of fine lines and wrinkles.
- Ceramide NP, Panthenol, Squalane – strengthen the skin barrier and provide hydration.
Benefits
- Accelerates skin renewal
- Improves elasticity and firmness
- Smooths rough skin texture
- Helps reduce enlarged pores
- Brightens uneven skin tone and pigmentation
- Supports post-acne mark improvement
- Strengthens the skin barrier
- Provides gentle exfoliation and resurfacing effects
Suitable For
- Aging or mature skin
- Enlarged pores
- Rough or uneven skin texture
- Post-acne marks and pigmentation
- Dull skin lacking firmness
- Skin with weakened barrier function
Directions for Use
- Apply at night as the final step of skincare.
- Use approximately 2–3 times per week, adjusting frequency according to skin tolerance.
- A mild prickling sensation is expected.
- Use sunscreen during the day, as exfoliation may increase sun sensitivity.
Ingredients: Maltodextrin, Squalane, Sodium DNA (PDRN), Madecassoside, Hydrolyzed Sponge (Spicule), Lactobacillus Extracellular Vesicles, Phaseolus Radiatus Seed Extract, Centella Asiatica Leaf Vesicles
Made in Korea


















